BDBM751467 US20250195699, Compound 6e

SMILES COc1ccccc1CCN4CCC(N(C(=O)C2CC=CO2)c3ccccc3)CC4

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 751467   

TargetMu-type opioid receptor(Human)
University of Michigan

US Patent
LigandPNGBDBM751467(US20250195699, Compound 6e)
Affinity DataKi:  0.200nMAssay Description:Binding affinities for fentanyl derivatives 1 and 6a-e at KOR, MOR, and DOR were determined by competitive displacement of [3H] diprenorphine as prev...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
University of Michigan

US Patent
LigandPNGBDBM751467(US20250195699, Compound 6e)
Affinity DataKi:  0.400nMAssay Description:Binding affinities for fentanyl derivatives 1 and 6a-e at KOR, MOR, and DOR were determined by competitive displacement of [3H] diprenorphine as prev...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDelta-type opioid receptor(Human)
University of Michigan

US Patent
LigandPNGBDBM751467(US20250195699, Compound 6e)
Affinity DataKi:  1.5nMAssay Description:Binding affinities for fentanyl derivatives 1 and 6a-e at KOR, MOR, and DOR were determined by competitive displacement of [3H] diprenorphine as prev...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetKappa-type opioid receptor(Human)
University of Michigan

US Patent
LigandPNGBDBM751467(US20250195699, Compound 6e)
Affinity DataKi:  7nMAssay Description:Binding affinities for fentanyl derivatives 1 and 6a-e at KOR, MOR, and DOR were determined by competitive displacement of [3H] diprenorphine as prev...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetKappa-type opioid receptor(Human)
University of Michigan

US Patent
LigandPNGBDBM751467(US20250195699, Compound 6e)
Affinity DataKi:  8nMAssay Description:Binding affinities for fentanyl derivatives 1 and 6a-e at KOR, MOR, and DOR were determined by competitive displacement of [3H] diprenorphine as prev...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDelta-type opioid receptor(Human)
University of Michigan

US Patent
LigandPNGBDBM751467(US20250195699, Compound 6e)
Affinity DataKi:  11nMAssay Description:Binding affinities for fentanyl derivatives 1 and 6a-e at KOR, MOR, and DOR were determined by competitive displacement of [3H] diprenorphine as prev...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent