BDBM75164 MLS001204421::N-[2-(3-Cyano-5,7-dimethyl-quinolin-2-ylamino)-ethyl]-2-methoxy-benzamide::N-[2-[(3-cyano-5,7-dimethyl-2-quinolinyl)amino]ethyl]-2-methoxybenzamide::N-[2-[(3-cyano-5,7-dimethyl-2-quinolyl)amino]ethyl]-2-methoxy-benzamide::N-[2-[(3-cyano-5,7-dimethyl-quinolin-2-yl)amino]ethyl]-2-methoxy-benzamide::N-[2-[(3-cyano-5,7-dimethylquinolin-2-yl)amino]ethyl]-2-methoxybenzamide::SMR000504666::cid_24747099
SMILES COc1ccccc1C(=O)NCCNc1nc2cc(C)cc(C)c2cc1C#N
InChI Key InChIKey=OYHKISDREVFLDF-UHFFFAOYSA-N
Data 3 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 75164
TargetCystic fibrosis transmembrane conductance regulator(Human)
University of Genoa
Curated by ChEMBL
University of Genoa
Curated by ChEMBL
Affinity DataEC50: 1.10E+4nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Human)
University of Genoa
Curated by ChEMBL
University of Genoa
Curated by ChEMBL
Affinity DataEC50: 1.10E+4nMAssay Description:Activity at human CFTR delta F508 mutant expressed in forskolin-stimulated FRT cells assessed as increase in iodine influx measured as decrease in YF...More data for this Ligand-Target Pair
Affinity DataEC50: 4.00E+4nMAssay Description:Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...More data for this Ligand-Target Pair