BDBM751725 6-methyl-2-morpholino-9-pyrazol-1-yl-4-(4-pyridylamino)pyrimido[5,4-c]quinolin-5-one ::US20250197375, Compound 65

SMILES Cn1c(=O)c2c(Nc3ccncc3)nc(N3CCOCC3)nc2c2cc(-n3cccn3)ccc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 751725   

LigandPNGBDBM751725(6-methyl-2-morpholino-9-pyrazol-1-yl-4-(4-pyridyla...)
Affinity DataIC50: 55nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

LigandPNGBDBM751725(6-methyl-2-morpholino-9-pyrazol-1-yl-4-(4-pyridyla...)
Affinity DataIC50: 5.50E+3nMAssay Description:Genetic or pharmacological disruption of PIKfyve activity results in enlargement of endosomal vesicles. This enlargement was utilized as a surrogate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent