BDBM752285 7-(2-Amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-4-(2-fluoro-5-(trifluoromethoxy)benzyl)-3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-one 1::US20250197390, Example 1

SMILES Nc1nc2cc(-c3ccc4c(c3)C(=O)N(Cc3cc(OC(F)(F)F)ccc3F)CCO4)ccn2n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 752285   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandPNGBDBM752285(7-(2-Amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-4-(...)
Affinity DataIC50: 23nMAssay Description:The ADP GLO method was used for detecting the inhibitory activities of the compounds of the present disclosure against RIPK1 kinase. The method is sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
10/14/2025
Entry Details
US Patent