BDBM752343 (1R,3S,5R)-2-(2-(3-acetyl- 7-methyl-5-(2-methylpyr- imidin-5-yl)-1H-pyrrolo [2,3-c]pyridin-1-yl)acetyl)- N-(6-bromo-3-chloropyr- idin-2-yl)-5-methyl-2-aza- bicyclo[3.1.0]hexane-3- carboxamide::US20250197403, Compound 21

SMILES CC(=O)c1cn(CC(=O)N2[C@H](C(=O)Nc3nc(Br)ccc3Cl)C[C@@]3(C)C[C@@H]23)c2c(C)nc(-c3cnc(C)nc3)cc12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 752343   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM752343((1R,3S,5R)-2-(2-(3-acetyl- 7-methyl-5-(2-methylpyr...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent