BDBM752513 US20250197406, Example 104

SMILES CC(C)Nc1c(F)c(C(F)(F)F)c(-c2cn3cc(NC(=O)[C@@H]4C[C@@H]4CO)nc3cn2)c2cn[nH]c12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 752513   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
1ST Biotherapeutics

US Patent
LigandPNGBDBM752513(US20250197406, Example 104)
Affinity DataIC50: 100nMAssay Description:HPK1 kinase activity was measured by Promega's ADP-Glo™ kinase assay. In this assay, 5 ng of recombinant human HPK1 (signalchem) is incubated wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent