BDBM752544 US20250197406, Example 135

SMILES CC(=O)Nc1cn2cc(-c3c(Cl)c(F)c([C@@H](C)N[S@](=O)C(C)(C)C)c4[nH]ncc34)ncc2n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 752544   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
1ST Biotherapeutics

US Patent
LigandPNGBDBM752544(US20250197406, Example 135)
Affinity DataIC50: 100nMAssay Description:HPK1 kinase activity was measured by Promega's ADP-Glo™ kinase assay. In this assay, 5 ng of recombinant human HPK1 (signalchem) is incubated wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent