BDBM752801 US20250197424, Compound 13a''

SMILES CCc1cccc2cc(O)cc(-c3c(F)c4c5c(nc(OC[C@@]67CCCN6C[C@H](F)C7)nc5c3F)N3CC5CCC(N5)[C@@H]3CCO4)c12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 752801   

TargetGTPase KRas [G12D]/Son of sevenless homolog 1 [564-1049](Human)
Shanghai Pharmaceuticals Holding Co.

US Patent
LigandPNGBDBM752801(US20250197424, Compound 13a')
Affinity DataIC50: 28.2nMAssay Description:a) BI-2852 was used as a positive control, with its stock solution as the first dilution point, followed by a 3-fold dilution, making a total of 10+0...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent