BDBM752823 US20250197424, Compound 28b

SMILES CCc1cccc2cc(O)cc(-c3c(F)c4c5c(nc(OC[C@]67C[C@@H](F)CN6C[C@@H](CN6CCOCC6)C7)nc5c3F)N3CC5CCC(N5)[C@@H]3CO4)c12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 752823   

TargetGTPase KRas [G12D]/Son of sevenless homolog 1 [564-1049](Human)
Shanghai Pharmaceuticals Holding Co.

US Patent
LigandPNGBDBM752823(US20250197424, Compound 28b)
Affinity DataIC50: 15.2nMAssay Description:a) BI-2852 was used as a positive control, with its stock solution as the first dilution point, followed by a 3-fold dilution, making a total of 10+0...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent