BDBM752855 US20250197425, Example 31

SMILES CC[C@H](Nc1nc(N[C@H]2CCN(S(=O)(=O)c3cnn(C)c3)C2)c2ncn(C(C)C)c2n1)[C@@H](C)O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 752855   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-D1(Human)
Astrazeneca

US Patent
LigandPNGBDBM752855(US20250197425, Example 31)
Affinity DataIC50: 39nMAssay Description:Compounds were tested in breast cancer cell line MCF-7 to assess inhibition of CDK1, CDK2, and CDK4 activity. MCF-7 cells transiently transfected wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/15/2025
Entry Details
US Patent

LigandPNGBDBM752855(US20250197425, Example 31)
Affinity DataIC50: 6.29E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/15/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Astrazeneca

US Patent
LigandPNGBDBM752855(US20250197425, Example 31)
Affinity DataIC50: 2.97E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/15/2025
Entry Details
US Patent