BDBM752857 US20250197425, Example 33

SMILES CC(C)[C@H](CO)Nc1nc(N[C@@H]2CN(S(C)(=O)=O)C[C@H]2F)c2ncn(C(C)C)c2n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 752857   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-D1(Human)
Astrazeneca

US Patent
LigandPNGBDBM752857(US20250197425, Example 33)
Affinity DataIC50: 26nMAssay Description:Compounds were tested in breast cancer cell line MCF-7 to assess inhibition of CDK1, CDK2, and CDK4 activity. MCF-7 cells transiently transfected wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/15/2025
Entry Details
US Patent

LigandPNGBDBM752857(US20250197425, Example 33)
Affinity DataIC50: 5.75E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/15/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Astrazeneca

US Patent
LigandPNGBDBM752857(US20250197425, Example 33)
Affinity DataIC50: 8.10E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/15/2025
Entry Details
US Patent