BDBM752935 N-(2-(4,4-difluoropiperidin-1-yl)-6-methylpyrimidin-4-yl)-4-((2-hydroxyethyl)sulfonamido)-2-((1S,6R)-6-(methoxymethyl)-3-azabicyclo[4.1.0]heptan-3-yl)benzamide (Example 49a) and N-(2-(4,4-difluoropiperidin-1-yl)-6-methylpyrimidin-4-yl)-4-((2-hydroxyethyl)sulfonamido)-2-((1R,6S)-6-(methoxymethyl)-3-azabicyclo[4.1.0]heptan-3-yl)benzamide (Example 49b)::US20250197428, Example 49b

SMILES CCOC(=O)CS(=O)(=O)Nc5ccc(C(=O)Nc2cc(C)nc(N1CCC(F)(F)CC1)n2)c(N4CC[C@]3(COC)CC3C4)c5

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 752935   

TargetKinesin-like protein KIF18A(Human)
Accent Therapeutics

US Patent
LigandPNGBDBM752935(N-(2-(4,4-difluoropiperidin-1-yl)-6-methylpyrimidi...)
Affinity DataIC50: 100nMAssay Description:A KIF18A ATPase assay was performed in small-volume, nonbinding, 384-well white plates at a final volume of 10 μL/well. Test compounds (10 mM solutio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
10/15/2025
Entry Details
US Patent