BDBM753216 US12338220, Example 214

SMILES Cn1nc(C(=O)NCc2ccc(Cl)cc2)c2c1C(=O)N(CC1(S(=O)(=O)C(C)(C)[C@H](N)CO)CC1)CC2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 753216   

TargetDNA polymerase(HHV-5)
Gilead Sciences

US Patent
LigandPNGBDBM753216(US12338220, Example 214)
Affinity DataIC50: 3nMAssay Description:DNA polymerase activity was measured using a molecular beacon-based assay, as described in Ma et. al. 100 pM CMV polymerase or 625 pM HSV polymerase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/17/2025
Entry Details
US Patent

TargetDNA polymerase catalytic subunit(HHV-1)
Gilead Sciences

US Patent
LigandPNGBDBM753216(US12338220, Example 214)
Affinity DataIC50: 32nMAssay Description:DNA polymerase activity was measured using a molecular beacon-based assay, as described in Ma et. al. 100 pM CMV polymerase or 625 pM HSV polymerase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/17/2025
Entry Details
US Patent