BDBM753468 (S)-quinuclidin-3-yl (6''-(4-cyclopropylphenyl)-3'',4''-dihydro-1''H-spiro[cyclopropane-1,2''-naphthalen]-1''-yl)carbamate::US12338237, Example 226

SMILES O=C(NC1c2ccc(-c3ccc(C4CC4)cc3)cc2CCC12CC2)O[C@H]1CN2CCC1CC2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 753468   

TargetCeramide glucosyltransferase(Human)
Yuhan

US Patent
LigandPNGBDBM753468((S)-quinuclidin-3-yl (6'-(4-cyclopropylphenyl)-3',...)
Affinity DataIC50: 0.930nMAssay Description:(1) MaterialsA549 cells (ATCC, CCL-185)NBD C6-ceramide (Thermo Fisher, N1154)UDP-glucose (Sigma, U4625)Potassium chloride (Sigma, P9333)UltraPure™ 0....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/17/2025
Entry Details
US Patent