BDBM753569 6-isobutoxy-4-(6-(6-((6-methoxypyridin-3-yl)methyl)-3,6-diazabicyclo[3.3.1]heptan-3-yl)pyridin-3-yl)-1H-pyrazolo[3'',4'':3,4]pyrazolo[1,5-a]pyridine ::US12338253, Compound 39

SMILES COc1ccc(CN2C3CC2CN(c2ccc(-c4cc(OCC(C)C)cn5nc6[nH]ncc6c45)cn2)C3)cn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 753569   

LigandPNGBDBM753569(6-isobutoxy-4-(6-(6-((6-methoxypyridin-3-yl)methyl...)
Affinity DataIC50: 0.300nMAssay Description:1.3 Preparation of 1× Kinase Buffer4 volume of distilled water was added to 1 volume of enzyme buffer 5×; 5 mM MgCl2; 1 mM DTT.1.4 Screening Methoda)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM753569(6-isobutoxy-4-(6-(6-((6-methoxypyridin-3-yl)methyl...)
Affinity DataIC50: 0.400nMAssay Description:1.3 Preparation of 1× Kinase Buffer4 volume of distilled water was added to 1 volume of enzyme buffer 5×; 5 mM MgCl2; 1 mM DTT.1.4 Screening Methoda)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM753569(6-isobutoxy-4-(6-(6-((6-methoxypyridin-3-yl)methyl...)
Affinity DataIC50: 30.5nMAssay Description:1.3 Preparation of 1× Kinase Buffer4 volume of distilled water was added to 1 volume of enzyme buffer 5×; 5 mM MgCl2; 1 mM DTT.1.4 Screening Methoda)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent