BDBM753574 6-(benzyloxy)-4-(6-(6-((6-methoxypyridin-3-yl)methyl)-3,6-diazabicyclo[3.3.1]heptan-3-yl)pyridin-3-yl)-1H-pyrazolo[3'',4'':3,4]pyrazolo[1,5-a]pyridine ::US12338253, Compound 3

SMILES COc8ccc(CN1C7CC1CN(c6ccc(c4cc(OCc2ccccc2)cn5nc3[nH]ncc3c45)cn6)C7)cn8

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 753574   

TargetProto-oncogene tyrosine-protein kinase receptor Ret [G810R](Human)
Applied Pharmaceutical Science

US Patent
LigandPNGBDBM753574(6-(benzyloxy)-4-(6-(6-((6-methoxypyridin-3-yl)meth...)
Affinity DataIC50: 16.2nMAssay Description:1.3 Preparation of 1× Kinase Buffer4 volume of distilled water was added to 1 volume of enzyme buffer 5×; 5 mM MgCl2; 1 mM DTT.1.4 Screening Methoda)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/17/2025
Entry Details
US Patent