BDBM753578 6-(4-fluorobutoxy)-4-(6-(6-((6-methoxypyridin-3-yl)methyl)-3,6-diazabicyclo[3.3.1]heptan-3-yl)pyridin-3-yl)-1H-pyrazolo[3'',4'':3,4]pyrazolo[1,5-a]pyridine ::US12338253, Compound 13

SMILES COc1ccc(CN2C3CC2CN(c2ccc(-c4cc(OCCCCF)cn5nc6[nH]ncc6c45)cn2)C3)cn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 753578   

TargetProto-oncogene tyrosine-protein kinase receptor Ret [G810R](Human)
Applied Pharmaceutical Science

US Patent
LigandPNGBDBM753578(6-(4-fluorobutoxy)-4-(6-(6-((6-methoxypyridin-3-yl...)
Affinity DataIC50: 3.10nMAssay Description:1.3 Preparation of 1× Kinase Buffer4 volume of distilled water was added to 1 volume of enzyme buffer 5×; 5 mM MgCl2; 1 mM DTT.1.4 Screening Methoda)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/17/2025
Entry Details
US Patent