BDBM753585 (4-(5-(6-(2-fluoroethoxy)-1H-pyrazolo[3'',4'':3,4]pyrazolo[1,5-a]pyridin-4-yl)pyridin-2-yl)piperazin-1-yl)(6-methoxypyridin-3-yl)methanone ::US12338253, Compound 22

SMILES COc1ccc(C(=O)N2CCN(c3ccc(-c4cc(OCCF)cn5nc6[nH]ncc6c45)cn3)CC2)cn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 753585   

TargetProto-oncogene tyrosine-protein kinase receptor Ret [G810R](Human)
Applied Pharmaceutical Science

US Patent
LigandPNGBDBM753585((4-(5-(6-(2-fluoroethoxy)-1H-pyrazolo[3',4':3,4]py...)
Affinity DataIC50: 1.70nMAssay Description:1.3 Preparation of 1× Kinase Buffer4 volume of distilled water was added to 1 volume of enzyme buffer 5×; 5 mM MgCl2; 1 mM DTT.1.4 Screening Methoda)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/17/2025
Entry Details
US Patent