BDBM75446 2-Methoxy-N-(5-thiophen-2-yl-[1,3,4]thiadiazol-2-yl)-acetamide::2-methoxy-N-(5-thiophen-2-yl-1,3,4-thiadiazol-2-yl)acetamide::2-methoxy-N-(5-thiophen-2-yl-1,3,4-thiadiazol-2-yl)ethanamide::2-methoxy-N-[5-(2-thienyl)-1,3,4-thiadiazol-2-yl]acetamide::MLS000034756::SMR000005332::cid_649189

SMILES C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnccn23)cn1

InChI Key InChIKey=BGOHMAJTGWYSNO-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 75446   

TargetFibroblast growth factor receptor 2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 75446BDBM75446(6-(6-acrylamidopyridin-3-yl)-7-(4-((6-methylpyridi...)
Affinity DataIC50: 10nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 75446BDBM75446(6-(6-acrylamidopyridin-3-yl)-7-(4-((6-methylpyridi...)
Affinity DataIC50: 10nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 75446BDBM75446(6-(6-acrylamidopyridin-3-yl)-7-(4-((6-methylpyridi...)
Affinity DataIC50: 10nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent