BDBM75476 (2-amino-5-bromo-6-methyl-pyrimidin-4-yl)-(4-chlorophenyl)amine::5-bromanyl-N4-(4-chlorophenyl)-6-methyl-pyrimidine-2,4-diamine::5-bromo-4-N-(4-chlorophenyl)-6-methylpyrimidine-2,4-diamine::5-bromo-N4-(4-chlorophenyl)-6-methylpyrimidine-2,4-diamine::5-bromo-N~4~-(4-chlorophenyl)-6-methyl-2,4-pyrimidinediamine::MLS000327539::SMR000180460::cid_1487824

SMILES C=CC(=O)Nc1ccc(-c2c(-c3ccc(C(=O)N4CC5(CCC5)C4)cc3)c(C(N)=O)c3cnccn23)cc1

InChI Key InChIKey=VZWXOOIZMWYVNF-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 75476   

TargetFibroblast growth factor receptor 2(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75476BDBM75476(7-(4-(2-azaspiro[3.3]heptane-2-carbonyl)phenyl)-6-...)
Affinity DataIC50: 55nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75476BDBM75476(7-(4-(2-azaspiro[3.3]heptane-2-carbonyl)phenyl)-6-...)
Affinity DataIC50: 550nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75476BDBM75476(7-(4-(2-azaspiro[3.3]heptane-2-carbonyl)phenyl)-6-...)
Affinity DataIC50: 550nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent