BDBM754790 N-(4-(2-(((1r,4r)-4- aminocyclohexyl)- amino)-8-isopropyl-7- oxo-7,8-dihydropyrido- [2,3-d]pyrimidin-6- yl)-2,3,6-trifluoro- phenyl)-1-phenyl- methane sulfonamide::US12344603, Compound 56

SMILES CC(C)n1c(=O)c(-c2cc(F)c(NS(=O)(=O)Cc3ccccc3)c(F)c2F)cc2cnc(N[C@H]3CC[C@H](N)CC3)nc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 754790   

LigandPNGBDBM754790(N-(4-(2-(((1r,4r)-4- aminocyclohexyl)- amino)-8-is...)
Affinity DataIC50: 0.170nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent