BDBM754820 1-(2-fluorophenyl)-N- (2,3,6-trifluoro-4-(2- (((3S,5S)-5-fluoro- piperidin-3-yl)amino)- 8-isopropyl-7-oxo-7,8- dihydropyrido[2,3-d]- pyrimidin-6-yl)phenyl)- methanesulfonamide::US12344603, Compound 86

SMILES CC(C)n1c(=O)c(-c2cc(F)c(NS(=O)(=O)Cc3ccccc3F)c(F)c2F)cc2cnc(N[C@@H]3CNC[C@@H](F)C3)nc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 754820   

LigandPNGBDBM754820(1-(2-fluorophenyl)-N- (2,3,6-trifluoro-4-(2- (((3S...)
Affinity DataIC50: 0.160nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
10/22/2025
Entry Details
US Patent