BDBM754856 N-(2,6-difluoro-4-(8- isopropyl-2-(((1r,4r)- 4-((2-methoxyethyl)- (methyl)amino)cyclo- hexyl)amino)-7-oxo- 7,8-dihydropyrido[2,3- d]pyrimidin-6-yl)- phenyl)-1-(4-fluoro- phenyl)methanesulfon- amide::US12344603, Compound 122

SMILES COCCN(C)[C@H]1CC[C@H](Nc2ncc3cc(-c4cc(F)c(NS(=O)(=O)Cc5ccc(F)cc5)c(F)c4)c(=O)n(C(C)C)c3n2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 754856   

LigandPNGBDBM754856(N-(2,6-difluoro-4-(8- isopropyl-2-(((1r,4r)- 4-((2...)
Affinity DataIC50: 0.120nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
10/22/2025
Entry Details
US Patent