BDBM754891 3,3,3-trifluoro-N-(2- fluoro-4-(2-(((1r,4r)-4- ((2-fluoroethyl)(meth- yl)amino)cyclohexyl)- amino)-8-isopropyl-7- oxo-7,8-dihydropyrido- [2,3-d]pyrimidin-6-yl)- phenyl)propane-1-sul- fonamide::US12344603, Compound 157

SMILES CC(C)n1c(=O)c(-c2ccc(NS(=O)(=O)CCC(F)(F)F)c(F)c2)cc2cnc(N[C@H]3CC[C@H](N(C)CCF)CC3)nc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 754891   

LigandPNGBDBM754891(3,3,3-trifluoro-N-(2- fluoro-4-(2-(((1r,4r)-4- ((2...)
Affinity DataIC50: 0.140nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent