BDBM754897 N-4-(2-(((1r,4r)-4- (dimethylamino)cyclo- hexyl)amino)-8- isopropyl-7-oxo-7,8- dihydropteridin-6-yl)- 2-fluorophenyl)-2,2- difluorobutane-1-sulfon- amide hydrochloride::US12344603, Compound 165

SMILES CCC(F)(F)CS(=O)(=O)Nc1ccc(-c2nc3cnc(N[C@H]4CC[C@H](N(C)C)CC4)nc3n(C(C)C)c2=O)cc1F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 754897   

LigandPNGBDBM754897(N-4-(2-(((1r,4r)-4- (dimethylamino)cyclo- hexyl)am...)
Affinity DataIC50: 0.100nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent