BDBM754902 1-p-tolyl-N-(2,3,6- trifluoro-4-(2-(((3S,5S)- 5-fluoropiperidin-3- yl)amino)-8-isopropyl- 7-oxo-7,8-dihydro- pteridin-6-yl)phenyl)- methanesulfonamide hydrochloride::US12344603, Compound 170

SMILES Cc1ccc(CS(=O)(=O)Nc2c(F)cc(-c3nc4cnc(N[C@@H]5CNC[C@@H](F)C5)nc4n(C(C)C)c3=O)c(F)c2F)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 754902   

LigandPNGBDBM754902(1-p-tolyl-N-(2,3,6- trifluoro-4-(2-(((3S,5S)- 5-fl...)
Affinity DataIC50: 0.130nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
10/22/2025
Entry Details
US Patent