BDBM754913 N-(4-(2-((4-(dimethyl- amino)-3-fluorocyclo- hexyl)amino)-8- isopropyl-7-oxo-7,8- dihydropteridin-6-yl)- 2-fluorophenyl)-1-(4- fluorophenyl)methane- sulfonamide::US12344603, Compound 181

SMILES CC(C)n1c(=O)c(-c2ccc(NS(=O)(=O)Cc3ccc(F)cc3)c(F)c2)nc2cnc(NC3CCC(N(C)C)C(F)C3)nc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 754913   

LigandPNGBDBM754913(N-(4-(2-((4-(dimethyl- amino)-3-fluorocyclo- hexyl...)
Affinity DataIC50: 0.160nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent