BDBM754915 N-(2-fluoro-4-(2- (((1r,4r)-4-((2-fluoro- ethyl)(methyl)amino)- cyclohexyl)amino-8- isopropyl-7-oxo-7,8- dihydropteridin-6-yl)- phenyl)-1-phenyl- methanesulfonamide::US12344603, Compound 183

SMILES CC(C)n1c(=O)c(-c2ccc(NS(=O)(=O)Cc3ccccc3)c(F)c2)nc2cnc(N[C@H]3CC[C@H](N(C)CCF)CC3)nc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 754915   

LigandPNGBDBM754915(N-(2-fluoro-4-(2- (((1r,4r)-4-((2-fluoro- ethyl)(m...)
Affinity DataIC50: 0.120nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
10/22/2025
Entry Details
US Patent