BDBM754917 1-phenyl-N-(2,3,6- trifluoro-4-(2-(((3S,5S)- 5-fluoropiperidin-3-yl)- amino)-8-isopropyl-7- oxo-7,8-dihydropter- idin-6-yl)phenyl)- methanesulfonamide::US12344603, Compound 185

SMILES CC(C)n5c(=O)c(c2cc(F)c(NS(=O)(=O)Cc1ccccc1)c(F)c2F)nc4cnc(N[C@@H]3CCC[C@@H](F)C3)nc45

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 754917   

LigandPNGBDBM754917(1-phenyl-N-(2,3,6- trifluoro-4-(2-(((3S,5S)- 5-flu...)
Affinity DataIC50: 0.170nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
10/22/2025
Entry Details
US Patent