BDBM754936 N-(4-(2-(((1,4-trans)-4- (ethyl(methyl)amino)- cyclohexyl)amino)-8- isopropyl-7-oxo-7,8- dihydropyrido[2,3-d]- pyrimidin-6-yl)-2- fluorophenyl)-3,3,3- trifluoropropane-1- sulfonamide::US12344603, Compound 205

SMILES CCN(C)[C@H]1CC[C@H](Nc2ncc3cc(-c4ccc(NS(=O)(=O)CCC(F)(F)F)c(F)c4)c(=O)n(C(C)C)c3n2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 754936   

LigandPNGBDBM754936(N-(4-(2-(((1,4-trans)-4- (ethyl(methyl)amino)- cyc...)
Affinity DataIC50: 0.140nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
10/22/2025
Entry Details
US Patent