BDBM754944 3,3,3-Trifluoro-N-(2- fluoro-4-(8-isopropyl- 2-(((1,4-trans)-4- morpholinocyclohexyl)- amino)-7-oxo-7,8- dihydropyrido[2,3-d]- pyrimidin-6-yl)phenyl)- propane-1-sulfonamide::US12344603, Compound 213

SMILES CC(C)n1c(=O)c(-c2ccc(NS(=O)(=O)CCC(F)(F)F)c(F)c2)cc2cnc(N[C@H]3CC[C@H](N4CCOCC4)CC3)nc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 754944   

LigandPNGBDBM754944(3,3,3-Trifluoro-N-(2- fluoro-4-(8-isopropyl- 2-(((...)
Affinity DataIC50: 0.140nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
10/22/2025
Entry Details
US Patent