BDBM754976 N-[4-[2-[[4-(dimethyl- amino)cyclohexyl]- amino]-8-isopropyl-7- oxo-pteridin-6-yl]-2,6- difluoro-phenyl]-1-(4- fluorophenyl)methane- sulfonamide::US12344603, Compound 245

SMILES CC(C)n1c(=O)c(-c2cc(F)c(NS(=O)(=O)Cc3ccc(F)cc3)c(F)c2)nc2cnc(N[C@H]3CC[C@H](N(C)C)CC3)nc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 754976   

LigandPNGBDBM754976(N-[4-[2-[[4-(dimethyl- amino)cyclohexyl]- amino]-8...)
Affinity DataIC50: 0.100nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
10/22/2025
Entry Details
US Patent