BDBM754999 N-(4-[2-[[4-(dimethyl- amino)cyclohexyl]- amino]-8-isopropyl-7- oxo-pteridin-6-yl]-2- fluoro-phenyl]-1-indan- 2-yl-methanesulfon- amide::US12344603, Compound 268

SMILES CC(C)n1c(=O)c(-c2ccc(NS(=O)(=O)CC3Cc4ccccc4C3)c(F)c2)nc2cnc(N[C@H]3CC[C@H](N(C)C)CC3)nc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 754999   

LigandPNGBDBM754999(N-(4-[2-[[4-(dimethyl- amino)cyclohexyl]- amino]-8...)
Affinity DataIC50: 0.100nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent