BDBM755023 (5S)-8,9-dichloro-7-(2-fluoro-5-hydroxy-phenyl)-5-methyl-5H-pyrimido[1,2-a][1,4]benzodiazepin-3-one::US12344614, Example 5

SMILES C[C@@H]1N=C(c2cc(O)ccc2F)c2c(ccc(Cl)c2Cl)-n2ccc(=O)nc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 755023   

LigandPNGBDBM755023((5S)-8,9-dichloro-7-(2-fluoro-5-hydroxy-phenyl)-5-...)
Affinity DataKi:  0.390nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandPNGBDBM755023((5S)-8,9-dichloro-7-(2-fluoro-5-hydroxy-phenyl)-5-...)
Affinity DataKi:  1.40nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandPNGBDBM755023((5S)-8,9-dichloro-7-(2-fluoro-5-hydroxy-phenyl)-5-...)
Affinity DataKi:  3.30nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandPNGBDBM755023((5S)-8,9-dichloro-7-(2-fluoro-5-hydroxy-phenyl)-5-...)
Affinity DataKi:  255nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent