BDBM755035 4-fluoro-3-[(4S)-7-chloro-1,4-dimethyl-8-(trifluoromethyl)-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-6-yl]phenol::US12344614, Example 17

SMILES Cc1nnc2n1-c1ccc(C(F)(F)F)c(Cl)c1C(c1cc(O)ccc1F)=N[C@H]2C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 755035   

LigandPNGBDBM755035(4-fluoro-3-[(4S)-7-chloro-1,4-dimethyl-8-(trifluor...)
Affinity DataKi:  0.990nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755035(4-fluoro-3-[(4S)-7-chloro-1,4-dimethyl-8-(trifluor...)
Affinity DataKi:  1.75nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755035(4-fluoro-3-[(4S)-7-chloro-1,4-dimethyl-8-(trifluor...)
Affinity DataKi:  68.8nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent