BDBM755044 5-chloro-6-[(4S)-7-chloro-1,4-dimethyl-8-(trifluoromethyl)-4H-imidazo[1,2-a][1,4]benzodiazepin-6-yl]pyridin-2-ol::US12344614, Example 26

SMILES Cc1cnc2n1-c1ccc(C(F)(F)F)c(Cl)c1C(c1nc(O)ccc1Cl)=N[C@H]2C

InChI Key

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 755044   

LigandPNGBDBM755044(5-chloro-6-[(4S)-7-chloro-1,4-dimethyl-8-(trifluor...)
Affinity DataKi:  3.25nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755044(5-chloro-6-[(4S)-7-chloro-1,4-dimethyl-8-(trifluor...)
Affinity DataKi:  7.88nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755044(5-chloro-6-[(4S)-7-chloro-1,4-dimethyl-8-(trifluor...)
Affinity DataKi:  20.5nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755044(5-chloro-6-[(4S)-7-chloro-1,4-dimethyl-8-(trifluor...)
Affinity DataKi:  6.73E+3nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent