BDBM755139 US20250213571, Compound 91

SMILES CNc1cc2nc3c(cnn13)C(=O)N[C@H](CO)COCc1cc(c3nnn(C)c3c1)N2

InChI Key

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 755139   

LigandPNGBDBM755139(US20250213571, Compound 91)
Affinity DataKd: <10nMAssay Description:Binding constants for the compounds described herein against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Discov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandPNGBDBM755139(US20250213571, Compound 91)
Affinity DataKd:  505nMAssay Description:Binding constants for the compounds described herein against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Discov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [583-855](Human)
Alumis

US Patent
LigandPNGBDBM755139(US20250213571, Compound 91)
Affinity DataKd:  5.50E+3nMAssay Description:Binding constants for the compounds described herein against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Discov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent