BDBM755168 US20250213705, Compound 48

SMILES CC(=O)NCCOCCOCCOCCC(=O)NC[C@H]1CC[C@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(=O)NCCCC[C@H](NC(=O)N[C@@H](CCc2n[nH]c(=O)o2)C(=O)O)C(=O)O)CC1

InChI Key

Data  1 KI  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 755168   

TargetGlutamate carboxypeptidase 2(Human)
Bright Peak Therapeutics

US Patent
LigandPNGBDBM755168(US20250213705, Compound 48)
Affinity DataKi:  73.5nMAssay Description:Prepare a working solution of 100 μM Amplex® Red reagent containing 0.25 U/mL HRP, 0.08 U/mL L-glutamate oxidase, 0.5 U/mL 1-glutamate-pyruvate trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

TargetGlutamate carboxypeptidase 2(Human)
Bright Peak Therapeutics

US Patent
LigandPNGBDBM755168(US20250213705, Compound 48)
Affinity DataKd:  1.65E+3nMAssay Description:The interaction of PSMA-binding variants with human FOLH1 was measured with Surface Plasmon Resonance (SPR) technology. Biotinylated FOLH1 was captur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

TargetGlutamate carboxypeptidase 2(Human)
Bright Peak Therapeutics

US Patent
LigandPNGBDBM755168(US20250213705, Compound 48)
Affinity DataIC50: 1.03E+4nMAssay Description:Prepare a working solution of 100 μM Amplex® Red reagent containing 0.25 U/mL HRP, 0.08 U/mL L-glutamate oxidase, 0.5 U/mL 1-glutamate-pyruvate trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent