BDBM755593 (3-((1H-pyrazolo[4,3-b]- pyridin-1-yl)methyl)bicyclo- [1.1.1]pentan-1-yl)(5-(3,5- difluorophenyl)-4,5-dihydro- 1H-pyrazol-1-yl)methanone::US20250214942, Example 65

SMILES O=C(N1N=CCC1c1cc(F)cc(F)c1)C12CC(Cn3ncc4ncccc43)(C1)C2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 755593   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755593((3-((1H-pyrazolo[4,3-b]- pyridin-1-yl)methyl)bicyc...)
Affinity DataIC50: 11nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
10/23/2025
Entry Details
US Patent