BDBM755594 1-((3-(5-(3,5-difluorophenyl)- 4,5-dihydro-1H-pyrazole-1- carbonyl)bicyclo[1.1.1]- pentan-1-yl)methyl)-1H- indazole-6-carbonitrile::US20250214942, Example 66

SMILES N#Cc1ccc2cnn(CC34CC(C(=O)N5N=CCC5c5cc(F)cc(F)c5)(C3)C4)c2c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 755594   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755594(1-((3-(5-(3,5-difluorophenyl)- 4,5-dihydro-1H-pyra...)
Affinity DataIC50: 16nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent