BDBM755701 1-((3-(5-(5-cyanopyridin-3- yl)-4,5-dihydro-1H-pyrazole- 1-carbonyl)bicyclo[1.1.1]- pentan-1-yl)methyl)-1H- indazole-5-carbonitrile::US20250214942, Example 173

SMILES N#Cc1ccc2c(cnn2CC23CC(C(=O)N4N=CCC4c4cncc(F)c4)(C2)C3)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 755701   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755701(1-((3-(5-(5-cyanopyridin-3- yl)-4,5-dihydro-1H-pyr...)
Affinity DataIC50: 9.10nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent