BDBM755734 1-((3-(2-(2-fluorophenyl)- azetidine-1-carbonyl)bicyclo- [1.1.1]pentan-1-yl)methyl)- 1H-indazole-5-carbonitrile::US20250214942, Example 248

SMILES N#Cc1ccc2c(cnn2CC23CC(C(=O)N4CCC4c4ccccc4F)(C2)C3)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 755734   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755734(1-((3-(2-(2-fluorophenyl)- azetidine-1-carbonyl)b...)
Affinity DataIC50: 23nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent