BDBM755750 4-((3-(5-(3,5-difluorophenyl)- 4,5-dihydro-1H-pyrazole-1- carbonyl)bicyclo[1.1.1]pentan- 1-yl)methoxy)-3-fluoro- benzonitrile::US20250214942, Example 333

SMILES N#Cc1ccc(OCC23CC(C(=O)N4N=CCC4c4cc(F)cc(F)c4)(C2)C3)c(F)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 755750   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755750(4-((3-(5-(3,5-difluorophenyl)- 4,5-dihydro-1H-pyr...)
Affinity DataIC50: 16nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent