BDBM755918 3-(5-(7-methyl-4-(pyrrolidin-1- ylmethyl)-7H-pyrrolo[2,3- d]pyrimidin-2-yl)-1-oxoisoindolin- 2-yl)piperidine-2,6-dione::US20250214991, Compound 184

SMILES Cn1ccc2c(CN3CCCC3)nc(-c3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)nc21

InChI Key InChIKey=VEFVRYUQZALTJR-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 755918   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
Oncopia Therapeutics, Inc. D/B/A/ Sk Life Science Labs

US Patent
LigandChemical structure of BindingDB Monomer ID 755918BDBM755918(3-(5-(7-methyl-4-(pyrrolidin-1- ylmethyl)-7H-pyrro...)
Affinity DataIC50: 65nMAssay Description:The binding potency was determined using HTRF assay technology (Perkin Elmer). Compounds were serially diluted in DMSO and 0.2 μL volume was transfer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent