BDBM755926 3-(5-(4-((2-oxa-7- azaspiro[3.5]nonan-7-yl)methyl)-1- (oxetan-3-yl)-1H-pyrrolo[2,3- b]pyridin-6-yl)-1-oxoisoindolin-2- yl)piperidine-2,6-dione::US20250214991, Compound 188

SMILES O=C1CCC(N2Cc3cc(-c4cc(CN5CCC6(CC5)COC6)c5ccn(C6COC6)c5n4)ccc3C2=O)C(=O)N1

InChI Key InChIKey=WOOZSNNGRRAFTN-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 755926   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
Oncopia Therapeutics, Inc. D/B/A/ Sk Life Science Labs

US Patent
LigandChemical structure of BindingDB Monomer ID 755926BDBM755926(3-(5-(4-((2-oxa-7- azaspiro[3.5]nonan-7-yl)methyl)...)
Affinity DataIC50: 65nMAssay Description:The binding potency was determined using HTRF assay technology (Perkin Elmer). Compounds were serially diluted in DMSO and 0.2 μL volume was transfer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent