BDBM755946 3-(1-oxo-5-(2-oxo-4-(pyrrolidin-1- ylmethyl)-2,3-dihydro-1H- pyrrolo[2,3-b]pyridin-6- yl)isoindolin-2-yl)piperidine-2,6- dione::US20250214991, Compound 200

SMILES O=C1CCC(N2Cc3cc(-c4cc(CN5CCCC5)c5c(n4)NC(=O)C5)ccc3C2=O)C(=O)N1

InChI Key InChIKey=CLRAYMAPEGSNDV-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 755946   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
Oncopia Therapeutics, Inc. D/B/A/ Sk Life Science Labs

US Patent
LigandChemical structure of BindingDB Monomer ID 755946BDBM755946(3-(1-oxo-5-(2-oxo-4-(pyrrolidin-1- ylmethyl)-2,3-d...)
Affinity DataIC50: 20nMAssay Description:The binding potency was determined using HTRF assay technology (Perkin Elmer). Compounds were serially diluted in DMSO and 0.2 μL volume was transfer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent