BDBM755968 3-(5-(3-amino-7-((tetrahydro-1H- furo[3,4-c]pyrrol-5(3H)- yl)methyl)-1H-pyrazolo[4,3- b]pyridin-5-yl)-1-oxoisoindolin-2- yl)piperidine-2,6-dione::US20250214991, Compound 214

SMILES Nc1n[nH]c2c(CN3CC4COCC4C3)cc(-c3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)nc12

InChI Key InChIKey=JDLIGRQSRGPCHF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 755968   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
Oncopia Therapeutics, Inc. D/B/A/ Sk Life Science Labs

US Patent
LigandChemical structure of BindingDB Monomer ID 755968BDBM755968(3-(5-(3-amino-7-((tetrahydro-1H- furo[3,4-c]pyrrol...)
Affinity DataIC50: 20nMAssay Description:The binding potency was determined using HTRF assay technology (Perkin Elmer). Compounds were serially diluted in DMSO and 0.2 μL volume was transfer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent