BDBM755978 (S)-3-(5-(1-methyl-4-(((R)- pyrrolidin-3-yl)oxy)-1H- pyrrolo[2,3-b]pyridin-6-yl)-1- oxoisoindolin-2-yl)piperidine-2,6- dione::US20250214991, Compound 219

SMILES Cn1ccc2c(O[C@@H]3CCNC3)cc(-c3ccc4c(c3)CN([C@H]3CCC(=O)NC3=O)C4=O)nc21

InChI Key InChIKey=GMDUACQWGCPJAZ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 755978   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
Oncopia Therapeutics, Inc. D/B/A/ Sk Life Science Labs

US Patent
LigandChemical structure of BindingDB Monomer ID 755978BDBM755978((S)-3-(5-(1-methyl-4-(((R)- pyrrolidin-3-yl)oxy)-1...)
Affinity DataIC50: 5.00E+3nMAssay Description:The binding potency was determined using HTRF assay technology (Perkin Elmer). Compounds were serially diluted in DMSO and 0.2 μL volume was transfer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent