BDBM756006 3-(5-(3-amino-1-(oxetan-3-yl)-7- (pyrrolidin-1-ylmethyl)-1H- pyrazolo[4,3-b]pyridin-5-yl)-1- oxoisoindolin-2-yl)piperidine-2,6- dione::US20250214991, Compound 234

SMILES Nc1nn(C2COC2)c2c(CN3CCCC3)cc(-c3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)nc12

InChI Key InChIKey=NRSXGRIVVGXVRK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 756006   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
Oncopia Therapeutics, Inc. D/B/A/ Sk Life Science Labs

US Patent
LigandChemical structure of BindingDB Monomer ID 756006BDBM756006(3-(5-(3-amino-1-(oxetan-3-yl)-7- (pyrrolidin-1-ylm...)
Affinity DataIC50: 5.00E+3nMAssay Description:The binding potency was determined using HTRF assay technology (Perkin Elmer). Compounds were serially diluted in DMSO and 0.2 μL volume was transfer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent