BDBM756054 3-(5-(2-cyclobutyl-4-(pyrrolidin-1- ylmethyl)-2H-pyrazolo[3,4- b]pyridin-6-yl)-1-oxoisoindolin-2- yl)piperidine-2,6-dione::US20250214991, Compound 316

SMILES N=C1N=C(c2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)C=C(CN2CCCC2)/C1=C/NC1CCC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 756054   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
Oncopia Therapeutics, Inc. D/B/A/ Sk Life Science Labs

US Patent
LigandPNGBDBM756054(3-(5-(2-cyclobutyl-4-(pyrrolidin-1- ylmethyl)-2H-p...)
Affinity DataIC50: 20nMAssay Description:The binding potency was determined using HTRF assay technology (Perkin Elmer). Compounds were serially diluted in DMSO and 0.2 μL volume was transfer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent